Document Type : Original Research Article
Authors
1
MSc Student, Department of Epidemiology, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran
2
MSc Student, Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran
3
Professor, Department of Epidemiology, Faculty of Health, Mashhad University of Medical Sciences, Mashhad, Iran
4
Assistant Professor, Department of Mathematics and Statistics, Macquarie University, Sydney, Australia
5
Assistant Professor, Department of Epidemiology, Faculty of Health, Mashhad University of Medical Sciences, Mashhad, Iran
6
Assistant Professor, Department of Epidemiology, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract
Background and aim: Breast cancer is top-ranking cancer among women regarding its incidence and mortality rates. This study aimed to explore the epidemiology and possible geographical distribution of breast cancer in the Khorasan Razavi province.
Methods: This cross-sectional study utilized data from the cancer registration system, focusing on patients registered from 2013 to 2017 in Khorasan Razavi Province. Information from clinical, pathological, and cytological evaluations, as well as death certificates, was collected. Sample size was determined through full enumeration, including all diagnosed patients. Statistical analyses were performed using Stata V. 14 and SPSS V. 20, incorporating mean ± SD and frequency reporting. Incidence rates, age-standardized rates, and geographic clustering were assessed using ArcMap V. 10.6.1 software.
Results: Over five years, 5553 patients with breast cancer were diagnosed. The average diagnosis age of the patients was 51.41 ± 12.94 years. The ASR between 2013 and 2017 was 54.3, 40.9, 44.8, 42.8, and 40, respectively, which revealed an almost decreasing trend. The highest rate of crude occurrence was in Bakharz followed by Sarakhas, Khalilabad, Torbet Jam, Chenaran, Golbahar, Bardaskan, Mehvelat, Fariman, Roshtkhar, Kalat, Khaf, Zaveh. Taybad had the lowest incident rate. Anselin Local Moran’s I test revealed that there is no identified significant cluster in the counties of Khorasan Razavi (P>0.05).
Conclusion: The study suggests a decreasing trend in breast cancer incidence, with the highest rates in the 40-49 age group. Recommendations include implementing screening and prevention measures, particularly targeting high-risk populations, to address this health concern.
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