Document Type : Original Research Article
Authors
1
a) PhD in Reproductive Health, Department of Reproductive Health and Midwifery, School of Nursing & Midwifery, Iran University of Medical Sciences, Tehran, Iran b) Department of Reproductive Health and Midwifery, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
2
Associate Professor, Department of Reproductive Health and Midwifery, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
3
Professor, Department of Biostatics, Faculty of Medical Science, Trbiat Modares University, Tehran, Iran
4
Associate Professor, Pharmacy and Pharmaceutical Sciences Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran
10.22038/jmrh.2023.73792.2153
Abstract
Background & aim: Stressors negatively affect sexual activity, and estrogen and progesterone increase female libido. Additionally, adiponectin increases hormone release, and turmeric increases serum adiponectin. Thus, this study examined how turmeric extracts affected serum adiponectin, sexual function, and steroid hormone profiles in stressed women.
Methods: In this randomized clinical trial, 57 women with moderate to severe stress and poor sexual function who visited the gynecology clinic of Shohaday-e Yaftabad Hospital from August until April 2020. Sampling was done by convenience method and then participants randomly assigned to the intervention and control groups. The intervention group used 300 mg of turmeric extract daily for 4 weeks, while the control group used a placebo containing 500 mg of starch. Adiponectin, estradiol, and progesterone levels were measured in all participants before and four weeks after the intervention. Tools used include the demographic form (7 items), Depression Anxiety Stress Scale (DASS) (21 items), and the Female Sexual Function Index (FSFI) (19 items). The paired t-test and the independent t-test were employed for data analysis by SPSS (version 14).
Results: Results showed a significant difference between the two groups in terms of post-intervention adiponectin (P<0.001), estradiol (P=0.006), and progesterone (P<0.001). However, the after-intervention prolactin level (P=0.647) demonstrated no significant difference between the two groups. In addition, the after-intervention sexual function scores indicated a significant difference between the two groups (P<0.001).
Conclusion: Turmeric can enhance sexual function and estradiol hormone profiling. As a result, women can improve their sexual lives by consuming turmeric-containing foods.
Keywords
Main Subjects
)