TY - JOUR ID - 12306 TI - The Use of Flaxseed in Gynecology: A Review Article JO - Journal of Midwifery and Reproductive Health JA - JMRH LA - en SN - AU - Sourinejad, Hadis AU - Raisi Dehkordi, Ziba AU - Beigi, Marjan AU - Adibmoghaddam, Elham AU - Hadian, Mohammad AD - PhD candidate in Reproductive Health, Student Research Committee, Department of Midwifery And Reproductive Health, Nursing and midwifery school, Isfahan University of Medical Sciences, Isfahan, Iran AD - Lecturer, Department of Midwifery, School of Nursing and Midwifery, Shahre Kord University of Medical Sciences, Shahre Kord, Iran AD - Lecturer, Department of Midwifery and Reproductive Health, Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran AD - PhD candidate in Reproductive Health, Student Research Committee, Nursing and midwifery school, Isfahan University of Medical Sciences, Isfahan, Iran AD - MSc in Food Science and Technology, Department of Food Science and Technology, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran Y1 - 2019 PY - 2019 VL - 7 IS - 2 SP - 1594 EP - 1614 KW - Flaxseed KW - Breast Neoplasm KW - hot flashes KW - Mastodynia KW - Ovarian neoplasm KW - Premenstrual Syndrome DO - 10.22038/jmrh.2019.31820.1345 N2 - Background & aim: Flaxseed is the richest source of lignan which is one of the main categories of phytoestrogens. In addition to the estrogenic and anti-estrogenic properties of lignan, it has non-hormonal properties as well. The treatment of menopausal hot flashes and cyclic mastalgia, the reduction in vasomotor symptoms and tumor cell growth and recurrence, the prevention of breast and ovarian cancer,  and the improvement of the symptoms of premenstrual syndrome are some of the indications of this plant. Therefore, the current study aimed to review the effect of flaxseed on the control of menopausal symptoms, premenstrual syndrome as well as breast and ovarian cancers. Methods: In this study, English keywords of mastalgia, mastodynia, ovarian neoplasm, ovarian cancer, breast neoplasm, breast cancer, hot flashes, premenstrual syndrome, flax, flaxseed, lignan, phytoestrogen, and linum usitatissimum along with their Persian equivalents were searched through databases incluing PubMed, Proquest, Scopus, Science Direct, Google Scholar, SID, and Magiran. All the selected articles were the clinical trials and case-control studies performed from 1991 to 2017. Finally, 30 English and 8 Persian studies were reviewed in this study. Results: The results obtained from most studies on this plant showed its positive effects on menopausal symptoms, breast cancer, mastalgia, and premenstrual syndrome. Conclusion: According to the results, it can be concluded that due to the high properties of this plant (i.e., the negligible side effects and safe use of it in recommended amounts), it can be used within the field of obstetrics and gynecology. UR - https://jmrh.mums.ac.ir/article_12306.html L1 - https://jmrh.mums.ac.ir/article_12306_44088131d9bef1cad59c36f7ad134142.pdf ER -