Factors Related to Sleep Quality in Women Undergoing Infertility Treatment: A Systematic Review

Document Type : Review Article

Authors

1 PhD Student of Reproductive Health, Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran

2 a) Associate Professor, Nursing and Midwifery Care Research Center, Mashhad University of Medical Sciences, Mashhad, Iran b) Department of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran

10.22038/jmrh.2024.78770.2357

Abstract

Background & aim: Considering the importance of sleep in fertility outcomes, the present study aimed to investigate the factors related to sleep quality in women undergoing infertility treatment.
Methods: This systematic review was conducted by performing a comprehensive search in English databases including PubMed, Scopus, ScienceDirect, and Google Scholar, as well as Persian databases including SID, Magiran, and IranDoc, using the keywords of “assisted reproductive technology,” “psychological factors,” “infertility factors,” “sleep quality,” and “female.” Relevant studies published between 2013 and 2024 were identified. After removing duplicates and screening the titles and abstracts, full texts that met the inclusion criteria were included in this review. The methodological quality of the included studies was assessed using Newcastle–Ottawa Scale. A qualitative synthesis approach was used for data analysis.
Results: Out of 544 retrieved articles, a total of 12 articles were included in this systematic review. The findings were classified into two main categories, of “psychological factors” and “infertility-related factors”. In the category of psychological factors, an inverse relationship was found between levels of stress, anxiety, and depression with sleep quality. Regarding infertility-related factors, five studies reported that variables such as type of infertility (primary), cause of infertility (female factor), longer duration of infertility (more than three years), type of treatment (invasive), and specific conditions such as polycystic ovary syndrome and irregular and abnormal menstruation are associated with poor sleep quality in women.
Conclusion: The results indicate that both psychological and infertility-related factors can significantly influence the sleep quality of infertile women.

Keywords

Main Subjects

References

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Journal of Midwifery and Reproductive Health
Volume 14, Issue 2
April 2026
Pages 5291-5302

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