Wernicke’s Encephalopathy in Hyperemesis Gravidarum: A Case Report

Articles in Press

Document Type : Case Report

Authors

Obstetrics and Gynecologist, Mashhad university of medical Science, Iran

10.22038/jmrh.2025.77383.2294

Abstract

Introduction: Wernicke’s encephalopathy (WE) can rarely happen in the background of hyperemesis gravidarum (HG). The most commonly known etiology for WE is chronic alcohol abuse. Hyperemesis gravidarum (HG) is one of the many etiologies of WE. herein, we reported a case of HG who presented with neurological symptoms and was subsequently diagnosed with WE.
Case presentation: We reported a case of WE in the background of HG in a 22 years old primary gravid woman, with a gestational age of about 15 weeks. The patient presented with ataxia, confusion, bilateral blare vision, and lower extremity weakness. She had normal vital signs and neurological examinations showed confusion and spatial, temporal, and personal disorientation. laboratory studies showed no abnormal findings. Due to the presence of hyperthyroidism, thyroid storm was another suspected differential diagnosis; however, the magnetic resonance imaging findings were indicative of WE. The patient received full recovery after high dose supplementation of thiamin.

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Journal of Midwifery and Reproductive Health

Articles in Press, Accepted Manuscript
Available Online from 26 April 2026

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