The Relationship between Anthropometric Indices and Lipid Profile in PCOS Women: A Comprehensive Study at Imam Reza Hospital Infertility Treatment Centre, 2023

Articles in Press

Document Type : Original Research Article

Authors

1 Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Nutritional Sciences, Faculty of Medicine Mashhad, Metabolic Syndrome Research Center, University of Medical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran

3 Women health research center, Faculty of Medicine, Masshad University of Medical Science, Mashhad, Iran

10.22038/jmrh.2024.79344.2372

Abstract

Background and aim: Infertility presents a formidable challenge to global public health, with polycystic ovary syndrome (PCOS) emerging as a prominent contributor. PCOS is associated with persistent health complications, such as a higher risk of metabolic syndrome, type 2 diabetes, and cardiovascular disease. Elevated body weight and central adiposity exacerbate the likelihood of anovulation and infertility in affected women. This study seeks to explore the potential relationship between anthropometric measurements and lipid profiles among infertile women with PCOS.
Methods: This observational cross-sectional study was conducted at the Milad Infertility Treatment Center in Imam Reza Hospital, Mashhad, Iran, between May 2023 and January 2024. The study enrolled a total of 280 married women aged 18–45 years who met specific inclusion criteria, specifically those diagnosed with both polycystic ovary syndrome (PCOS) and infertility. Participants were selected through random sampling. Statistical analysis was performed using the SPSS. Descriptive statistics were used to summarize the data, where inferential statistics included tests of significance with a threshold set at P < 0.05.
Results: The study comprised 280 participants. A significant positive correlation was found between normal Body Mass Index (BMI) and triglyceride levels (TG) (P-value = 0.030). Likewise, individuals with a BMI exceeding 30 (indicative of obesity) displayed a notable positive correlation with elevated TG levels (P-value = 0.035). Furthermore, a statistically significant positive correlation was observed between Waist-to-Height Ratio (WHtR) values exceeding 0.57 and elevated TG levels (P-value = 0.003).
Conclusion: PCOS women, characterized by diverse features, exhibited distinct lipid profiles. The intricate relationship observed between lipid metabolism and various PCOS traits may shed light on the heightened susceptibility to long-term cardiovascular complications. Regular monitoring of blood lipids and management of central obesity are imperative for women with PCOS.

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Journal of Midwifery and Reproductive Health

Articles in Press, Accepted Manuscript
Available Online from 26 April 2026

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