Obstetric Patients with Coronavirus Infection: Symptoms and Critical Illness and Mortality

Document Type : Original Research Article


1 Medical Doctor, Resident of Obstetrics & Gynecology, Maternal &Neonate Center, Mashhad University of Medical Sciences, Mashhad, Iran

2 Assistant Professor,Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran

3 Assistant Professor of Nursing, Nursing and Midwifery Care, Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

4 MSc in Midwifery, Department of Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran

5 Assistant Professor, Department of Obstetrics and Gynecology, Mashhad University of Medical Sciences, Mashhad, Iran



Background & aim: Infection with COVID-19 during pregnancy increased some of the complications such as preterm labor, Intensive Care Unit (ICU) admission, maternal mortality, and adverse neonatal outcome. The aim of the present study is to an evaluation of symptoms, critical illness, and mortality among pregnant patients with COVID-19.
Methods: In this descriptive retrospective study, pregnant women referred to Imam Reza Hospital between February 20th, 2020, and September 21st, 2022 with COVID-19 diagnoses were included in this study by census method. The patients were stratified into symptomatic mild, moderate, and severe, according to the National Institute of Health (NIH). Data analysis using SPSS 26 by Student's t-test, logistic regression, and chi-square test.
Results: Out of 460 pregnant women, sixteen symptoms were reported by the patients with dyspnea being the most frequent. Among the symptoms reported by the patients, in addition to dyspnea, cough, fever (p= 0.00), abdominal pain (p= 0.04), and chills (p= 0.03) were significantly more frequently observed among the ICU-admitted patients. The least common symptom was flank pain. Women with severe diseases who died were at significantly higher risk for fever, cough, and dyspnea. 116 (25.2%) had severe disease and were admitted to the ICU and 5.7% expired. 22.4% of patients admitted to the ICU died. Hospitalization in ICU is the most important predictor of death. (B=-22.286, p=.000).
Conclusion: The study indicates that pregnant women who experience symptoms such as fever, dyspnea, cough, chills, or abdominal pain are more susceptible to severe COVID-19.


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