1
Resident of Obstetrics and Gynecologist, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2
a) Assistant Professor, Supporting the Family and Youth of Population Research Core, Mashhad University of Medical Sciences, Mashhad, Iran b) Department of Obstetrics & Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3
Professor of Anesthesiology and Critical Care, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Background & aim: Wernicke’s encephalopathy (WE) is a rare but serious neurologic complication of hyperemesis gravidarum (HG). The most commonly known etiology for WE is chronic alcohol misuse. Hyperemesis gravidarum (HG) is one of the many etiologies of WE. In this paper, we report a case of HG who presented with neurological symptoms and was subsequently diagnosed with WE. Case report: A case of WE associated with HG in a 22 years old primary gravid woman, with a gestational age of 15 weeks and 4 days, is reported. The patient presented with ataxia, confusion, bilateral blurred vision, and lower extremity weakness. She had normal vital signs, and neurological examinations showed confusion and spatial, temporal, and personal disorientation. Laboratory studies showed no abnormal findings. Due to the presence of hyperthyroidism, thyroid storm was another suspected differential diagnosis; however, it was ruled out after further thyroid functioning test and brain magnetic resonance imaging (MRI). Conclusion: The MRI findings were indicative of WE. The patient received full recovery after high dose supplementation of thiamine.
Parvaneh Hosseini,M , Jalili,J , HajMollaRezaei,E and Amini,S . (2026). Wernicke’s Encephalopathy Associated With Hyperemesis Gravidarum: A Case Report. Journal of Midwifery and Reproductive Health, (), 1-4. doi: 10.22038/jmrh.2025.77383.2294
MLA
Parvaneh Hosseini,M , , Jalili,J , , HajMollaRezaei,E , and Amini,S . "Wernicke’s Encephalopathy Associated With Hyperemesis Gravidarum: A Case Report", Journal of Midwifery and Reproductive Health, , , 2026, 1-4. doi: 10.22038/jmrh.2025.77383.2294
HARVARD
Parvaneh Hosseini M, Jalili J, HajMollaRezaei E, Amini S. (2026). 'Wernicke’s Encephalopathy Associated With Hyperemesis Gravidarum: A Case Report', Journal of Midwifery and Reproductive Health, (), pp. 1-4. doi: 10.22038/jmrh.2025.77383.2294
CHICAGO
M Parvaneh Hosseini, J Jalili, E HajMollaRezaei and S Amini, "Wernicke’s Encephalopathy Associated With Hyperemesis Gravidarum: A Case Report," Journal of Midwifery and Reproductive Health, (2026): 1-4, doi: 10.22038/jmrh.2025.77383.2294
VANCOUVER
Parvaneh Hosseini M, Jalili J, HajMollaRezaei E, Amini S. Wernicke’s Encephalopathy Associated With Hyperemesis Gravidarum: A Case Report. JMRH. 2026;():1-4. doi: 10.22038/jmrh.2025.77383.2294
